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Dernières publications
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Dylan Moutachi, Janek Hyzewicz, Pauline Roy, Mégane Lemaitre, Damien Bachasson, et al.. Treadmill running and mechanical overloading improved the strength of the plantaris muscle in the dystrophin‐desmin double knockout (DKO) mouse. The Journal of Physiology, In press, ⟨10.1113/JP286425⟩. ⟨hal-04643936⟩
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Medhi Hassani, Dylan Moutachi, Mégane Lemaitre, Alexis Boulinguiez, Denis Furling, et al.. Beneficial effects of resistance training on both mild and severe mouse dystrophic muscle function as a preclinical option for Duchenne muscular dystrophy. PLoS ONE, 2024, 19, ⟨10.1371/journal.pone.0295700⟩. ⟨hal-04501283⟩
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Antonio Atalaia, Dagmar Wandrei, Nawel Lalout, Rachel Thompson, Adrian Tassoni, et al.. EURO-NMD registry: federated FAIR infrastructure, innovative technologies and concepts of a patient-centred registry for rare neuromuscular disorders. Orphanet Journal of Rare Diseases, 2024, 19 (1), pp.66. ⟨10.1186/s13023-024-03059-3⟩. ⟨hal-04460667⟩
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Florent Porquet, Lin Weidong, Kévin Jehasse, Hélène Gazon, Maria Kondili, et al.. Specific DMPK-promoter targeting by CRISPRi reverses myotonic dystrophy type 1-associated defects in patient muscle cells. Molecular Therapy - Nucleic Acids, 2023, 32, pp.857 - 871. ⟨10.1016/j.omtn.2023.05.007⟩. ⟨hal-04287597⟩
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Caroline Le Guiner, T Larcher, A Lafoux, G Toumaniantz, S Webb, et al.. Characterization of the muscular and cardiac diseases of the DMSXL mouse model, a transgenic mouse model for Myotonic Dystrophy type 1. American Society of Gene & Cell Therapy, May 2023, LOS ANGELES, United States. ⟨hal-04096181⟩
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Dylan Moutachi, Mégane Lemaitre, Clément Delacroix, Onnik Agbulut, Denis Furling, et al.. Valproic acid reduces muscle susceptibility to contraction‐induced functional loss but increases weakness in two murine models of Duchenne muscular dystrophy. Clinical and Experimental Pharmacology and Physiology, In press, ⟨10.1111/1440-1681.13804⟩. ⟨hal-04146953⟩
Chiffres clés
144
Publications avec texte intégral
Open Access
53 %
Mots clés
Diaphragm
Astrocyte
Mice
Cell culture model
CRISPR/Cas9
CONGENITAL MYATHENIC SYNDROME
RNA splicing
Glutamate
Gene editing
Transgenic mouse model
Muscular dystrophy
Myotonic dystrophy type 1
Gene Therapy
BIOLOGIE MOLECULAIRE
Myotonic Dystrophy
Exercise
Myostatin
PacBio
Desmin
CRISPRi
Antisense oligonucleotides
Cells
Glucocorticoids
Brain
Hypoxia
CTG repeat instability
Heart failure
Dystrophin
Expression
Cultured
Acetylcholinesterase knockout mouse
Intermediate filament
Animals
Myotonic Dystrophy Type 1
Mouse model
Quantitative microdialysis
Myotonic dystrophy
Motoneuron
Dynamin 2
CMS
PCR
Acute coronary syndrome
Centronuclear myopathy
Maximal force
AAV
Dilated cardiomyopathy
GABA
Brain dysfunction
Alternative splicing
RNA biology
Mouse models
Duchenne muscular dystrophy
Humans
Dystrophie Myotonique
Central nervous system
Myelin
ACETYLCHOLINESTERASE
Fibrosis
Autophagy
Aging
Myotonic Dystrophy type 1
GSK3
Trinucleotide Repeat Expansion
Muscle
DMSXL mice
ARN
Thérapie génique
Transcriptomics
Myotonic dystrophy mouse models
Long read sequencing
Genotype phenotype correlation
DMPK
Gene therapy
Cardiac muscle
Oligodendrocytes
Astrocytes
Skeletal muscle
Dystrophie myotonique
Therapy
Exercice
Glucocorticoid-receptor
MBNL
Antisense oligonucleotide
Endurance training
RNA interference
Male
Acetylcholinesterase deficiency
Cell model
Oligodendrocyte
CTG repeats
Transgenic mouse
Trinucleotide repeat expansion
DM1
KNOCKOUT MICE
Glial cells
CTG repeat contractions
Neuron
Heart
Cytoskeleton
Cell penetrating peptide