GIP/MZT1 proteins orchestrate nuclear shaping - Archive ouverte du site Alsace
Article Dans Une Revue (Article De Synthèse) Frontiers in Plant Science Année : 2014

GIP/MZT1 proteins orchestrate nuclear shaping

Résumé

The functional organization of the nuclear envelope (NE) is only just emerging in plants with the recent characterization of NE protein complexes and their molecular links to the actin cytoskeleton. The NE also plays a role in microtubule nucleation by recruiting gamma-Tubulin Complexes (gamma-TuCs) which contribute to the establishment of a robust mitotic spindle. gamma-tubulin Complex Protein 3 (GCP3)-interacting proteins (G I Ps) have been identified recently as integral components of gamma-TuCs. GIPs have been conserved throughout evolution and are also named MZT1 (mitotic-spindle organizing protein 1). This review focuses on recent data investigating the role of GIP/MZT1 at the NE, including insights from the study of GIP partners. It also uncovers new functions for GIP/MZT1 during interphase and highlights a current view of NE-associated components which are critical for nuclear shaping during both cell division and differentiation.
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Dates et versions

hal-00953715 , version 1 (06-11-2024)

Identifiants

Citer

Morgane Batzenschlager, E. Herzog, G. Houlné, A.-C. Schmit, Marie-Edith Chaboute. GIP/MZT1 proteins orchestrate nuclear shaping. Frontiers in Plant Science, 2014, 5, pp.29. ⟨10.3389/fpls.2014.00029⟩. ⟨hal-00953715⟩
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